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Cabin , the startup which has been running overnight trips on luxury buses between Los Angeles and San Francisco--aiming at digitally connected, tech-savvy consumers looking to move between the technology hubs--has re-launched its service, saying that it has "completely re-engineered" its buses and services. According to Cabin, its new "Cabin G2" buses include 54 percent larger cabins than its first generation fleet, and a fancy "bump cancellation system" which reduces the bumpiness of a passeng
An Acadia Pharmaceuticals drug that’s already approved for psychosis associated with Parkinson’s disease could soon be heading to an FDA review to expand the use of the drug to dementia patients. On Monday, Acadia (NASDAQ: ACAD ) reported that its drug, pimavanserin, met the goal of delaying relapse of psychosis in dementia patients compared to a placebo.
Former New York Yankees all star Alex Rodriguez is racking up quite an impressive batting average in his new career as an investor and has added Fitplan to his roster of portfolio companies. The Los Angeles-based workout app launched by Landon Hamilton and Cam Speck has closed on $4.5 million led by A-Rod and Corazon Capital, and has added new celebrity athlete trainers — including Rodriguez — to cover the needs of would-be sports stars and interested amateurs alike. “One of th
Uber has pulled the on-demand JUMP scooters it runs in San Diego from the city this week, over frustration over the city's new rules over dockless scooters, which include permits, fees, and data sharing requirements. Those new rules--which include a fixed fee over around $5000 and per-scooter charges of around $150 per device--is an attempt by San Diego to rein in rampant scooters in the city.
Office leases are one of companies’ largest expenses, and if your whole team is working from home with no clear end in sight, you may be wondering what to do about your lease.
The treatment landscape for lung cancer has shifted significantly over the past few years , and more changes could be on the way. At the World Conference on Lung Cancer in Barcelona this weekend a number of drug makers trotted out some of their latest advances in immunotherapy, targeted pills, drug combinations, and more. Xconomy rounded up some of the most noteworthy headlines and put them in context below.
Tocagen’s experimental gene therapy for brain cancer therapy has failed a late-stage test, sinking the biotech’s stock price below $1. San Diego’s Tocagen (NASDAQ: TOCA ), has been testing its drug in recurrent high-grade glioma, the most common and deadly type of brain cancer in adults. The company said Thursday that the drug combination, Toca 511 and Toca FC, didn’t prolong patient survival in the Phase 3 trial compared to chemotherapy, the standard treatment.
Aerospace startup Relativity Space Inc. will launch satellites built by Santa Clara-based Momentus into space on its 3D-printed Terran 1 rocket, according to a new agreement signed by the two companies Sept. 12.
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Aerospace startup Relativity Space Inc. will launch satellites built by Santa Clara-based Momentus into space on its 3D-printed Terran 1 rocket, according to a new agreement signed by the two companies Sept. 12.
Goop is cashing in on pseudoscience and, in the process, giving natural health practices a bad name. Krista Berlincourt, the co-founder and chief executive officer of a new startup, Kensh? Health , hopes she can take back the narrative. “We’re the antithesis of Goop,” Berlincourt, a fintech veteran who previously led marketing and product at Simple Finance, tells TechCrunch.
What's the best way to reach out and recruit diverse candidates for your technology company? It's not easy, which is why Los Angeles-based Divercity.io exists. we spoke with co-founder Chuka Ikokwu to learn more about the startup and how it's helping companies to recruit more diverse workers. Describe what Divercity.io is all about? Chuka Ikokwu: Divercity.io is an HR tech platform that makes it very easy for companies to source diverse talent.
Are any of these little lies worth worrying over? “He’s not in right now.” “I am going to the doctor at that time.” “I paid only two dollars a unit to your competitor.” Whether not true and used to avoid hurting someone’s feelings, or whether used to gain an advantage in a negotiation, these little business lies are acceptable because they achieve their intended result without actually hurting the other party.
The Walt Disney Studios , in Burbank, and technology giant Microsoft Corp. are in a new deal where the two will work together, where Disney will work with Microsoft on ways to create, produce and distribute content on the Microsoft Azure cloud platform, the companies announced on Friday morning. According to the companies, they are in a five year "innovation partnership" to develop 'scene-to-screen' content workflows, which will include a technology hub called The Walt Disney Studios StudioLAB.
This year’s Lasker Awards, the US’s most prestigious biomedical honor, are going to five scientists whose work led to a critical breast cancer treatment and significant basic research advances that have helped pave the way for immunotherapy. H. Michael Shepard, Dennis Slamon, and Axel Ullrich won the Lasker-DeBakey Clinical Medical Research Award for inventing trastuzumab (Herceptin) , the Genentech antibody drug for HER2-positive breast cancer, a form of the disease that afflicts more than 50,0
San Diego-based MemComputing , a startup working on high performance computing technology, says it has been selected to join the Air Force Research Laboratory's Catalyst Space Accelerator , being held in Colorado Springs, Colorado. According to MemComputing, it is working on software which uses physics principles and the logic and reasoning functions of the human brain.
I’m sure that every one of us who has been out in the business world for a few years can look back with perfect hindsight and name a few college courses that we should have taken. What’s more disconcerting to me is that I can name a few that aren’t usually even offered, resulting in more than a few students graduating ill-prepared for the real business world!
Wednesday, September 18, 2019 -- The Goddess Project Documentary Screening. Join us for a screening of "The Goddess Project" documentary here at Toolbox LA. Synopsis: Determined to empower the feminine voice, two filmmakers packed their lives into a school bus and hit the road for what became the most transformative adventure of their lives. Through powerful conversations with over 100 women from different walks of life, The Goddess Project gives an intimate look into the collective experience t
San Diego-based SGI-DNA , a biotech company which is developing synthetic genomics and dna data storage technology, announced this morning that it has raised $25M in its Series A funding round. The funding was led by Northpond Ventures, and also included Oxford Finance and BroadOak Capital partners. SGI-DNA said it has created a fully automated gene synthesis platform, which includes an instrument that converts digitized DNA code to biological entities.
Angel investors and venture capitalists don’t make equity investments in nonprofit good causes. The simple reason is that it’s impossible to make money for investors when the goal of the company is to not make money. Yet as an active angel investor, I still get this question on a regular basis, so I’ll try to outline the considerations in common-sense terms.
We’re used to protecting the information on our smartphones by keeping strong passwords and setting a lock screen. But fewer people know about the importance of protecting the information in their vehicles. Earlier this year, the automotive shopping website CarGurus asked 1,020 consumers questions about common security practices and the risks of connected cars.
Tuesday, September 17, 2019 -- The Role of Rebranding for Mand A and Growth. Learn how this oft-overlooked ingredient can drive valuation both pre-deal and post-deal and support revenue growth. Key topics include: How to recognize an obsolete or weak brand story (interactive workshop) Typical messaging mistakes innovative companies make 7 best practices to strategically refresh brand messaging Crossing the chasm between strategy and creative execution Before and after: rebranding results for mid
Santa Monica-based Fair , which offers up very flexible, subscription-based leases on used cars, has acquired the Canvas subscription car service, which was owned by Ford Motor Credit. Financial terms of the acquisition were not announced. According to Ford, existing customers of Canvas will be given an option to join Fair's service at the ends of their current vehicle subscription term.
An entrepreneur is literally “one who creates a new business.” The best new businesses are ones that have never been done before, so mastering creativity and recognizing creativity are key skills and mindsets. But how does one recognize and nurture creativity in a person or team? In researching this question, I reviewed a classic book by Bryan Mattimore, “ Idea Stormers: How to Lead and Inspire Creative Breakthroughs ,” which details eight attributes of the most creative people, which seem to ma
For decades, advanced lung cancer was a quick death sentence. That’s no longer a given, thanks in part to the arrival of immunotherapy. If a medical meeting in Barcelona this week was any indication, more help could be on the way. Targeted medicine isn’t new to lung cancer, but only a fraction of patients have the eligible mutations, such as EGFR and ALK, and thus have a chance to avoid chemotherapy and its toxic side effects.
Sunday, September 15, 2019 -- More/Medavoy brunchwork. You're invited to an unforgettable brunch with More/Medavoy Co-founding Partners Brian Medavoy and Erwin More. Enjoy an intimate conversation with Brian and Erwin, curated connections, a creative challenge, and pitch. over a healthy meal.
In my experience as an advisor to entrepreneurs, business startup founders most often point to a shortage of funds as the primary cause of their startup failure. Yet I often see evidence that points right back at the founder or business owner, attempting to maintain excessive power and influence over of the effort, leading to a wide range of problems and a dysfunctional team.
GlaxoSmithKline is acquiring a startup it helped launch in 2013 as part of an alliance with life sciences venture capital firm Avalon Ventures. Avalon said Tuesday that GSK (NYSE: GSK ) has agreed to buy the company, Sitari Pharmaceuticals, which has been developing a treatment for celiac disease. Sitari was the first of eight companies spun up through the partnership between the Southern California investment outfit and British pharma company.
Interested in hearing more about the technology community in Orange County? A newly launched podcast, Accelerate OC , recently launched a series of interviews from Orange County innovators, trendsetters, entrepreneurs, investors and community leaders, in a live radio show and podcast. The new podcast, run by serial entrepreneur Carey Ransom , so far has included such guests as Bill Carpou, the CEO of OCTANe; Dan Rodriguez, the CEO of Kareo; Andrew Lyon, the Founding Dean of the Fowler Engineerin
Irvine-based 174 Power Global , a utility-scale, solar energy company which is owned by Hanwha Group, said this morning that it has closed on construction financing for a $210M, 150MW solar power plant near Odessa, Texas. The company said construction and term debt is being provided by Credit Agricole Corporate and Investment Bank and the Korea Development Bank, and an eight-year "solar hedge" is being provided by J.P.
San Diego-based ZeaKal , a startup which is working on technology to improve the photosynthetic capacity and efficiency of plants, announced on Tuesday that it has raised $15M in a Series C funding round. The funding came from Canopy rivers, Finistere Ventures, and Middleland Capital. As part of the funding round, ZeaKal said that Paul Shickler, the former president of DuPont Pioneer, has joined the company as a part of its leadership team, working on driving strategy and partnership opportuniti
Los Angeles-based Vid , a startup developing a social video platform, announced late Monday that it has received a strategic investment from Ontology, a developer of blockchain technology. Financial terms of the investment were not announced. Vid--which has yet to launch its product--says it is developing a video journaling application, where data is secured through "zero-knowledge" encryption and which is powered by Blockchain.
Santa Monica-based MakeSense Labs , the startup behind Sense.Chat , a messaging app which lets users share cryptocurrency tokens and connect via audio and video chats, says it has added venture capitalist Tim Draper to its board of directors. Sense.Chat is led by founder and CEO Crystal Rose. According to Rose, the company's messaging system is the "first messaging system of its kind" utilizing blockchain technology.
Irvine-based Future Media , a digital marketing company, announced late Thursday that it has acquired Oak & Jackal , a direct-to-consumer maker of watches. Financial details of the acquisition were not announced. Future Media said the acquisition is its first foray into consumer sales. Oak & Jackal was originally launched and funded through an effort on Kickstarter , in June of 2016.
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